Fine-tune a Large Language Model (LLM) for conversations about cancer, along with potential evaluation metrics

Tiya Vaj
2 min readJun 29, 2024

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Fine-Tuning Process:

  1. Data Collection:
  • Gather a large corpus of text data relevant to cancer conversations. This could include:
  • Patient-doctor dialogues from consultations
  • Support group discussions
  • Online forums and Q&A platforms focusing on cancer
  • Ensure the data is high-quality, well-structured, and covers a broad range of cancer types, stages, and patient concerns.

2.Data Preprocessing:

  • Clean and pre-process the text data by removing irrelevant information, correcting typos, and ensuring factual accuracy with the help of medical professionals.
  • Annotate the data with relevant information like specific cancer types, treatment options, and emotional tones.

3.Model Selection:

  • Choose a pre-trained LLM like GPT-3 or Jurassic-1 Jumbo that demonstrates strong performance in text generation and comprehension tasks.

4.Fine-Tuning:

  • Fine-tune the LLM on the prepared cancer conversation dataset. This involves training the model to recognize specific cancer-related language patterns, medical terminology, and nuances of patient emotions.

5.Evaluation and Iteration:

  • Evaluate the fine-tuned model using appropriate metrics (see below).
  • Based on the evaluation results, iterate on the data selection, pre-processing, and fine-tuning process to improve performance.

Evaluation Metrics:

Since you’re dealing with sensitive medical information and potentially emotional conversations, a multi-faceted evaluation approach is necessary. Here are some key metrics to consider:

Factual Accuracy:

  • Precision: The proportion of the model’s responses that are medically accurate when compared to a ground truth database or expert review.
  • Recall: The proportion of factual inquiries the model addresses correctly out of all such inquiries from patients.

Conversational Coherence:

  • Bleu Score: Measures how similar the model’s responses are to human-generated reference conversations about cancer.
  • ROUGE Score: Evaluates how well the model incorporates relevant information from the conversation history into its responses.

Emotional Sensitivity:

  • Human Evaluation: Conduct user studies where patients interact with the conversational AI and assess their perception of the model’s empathy, understanding, and ability to address their concerns appropriately.
  • Sentiment Analysis: Evaluate how well the model recognizes and responds to the emotional tones present in patient conversations (e.g., fear, anxiety, hope).

Additional Considerations:

  • Bias Detection: Ensure the model’s responses are free from biases regarding demographics, socioeconomic status, or specific cancer types.
  • Safety and Transparency: Implement safeguards to prevent the model from providing medical advice or diagnoses. Be transparent about the model’s limitations and the importance of consulting a doctor for any medical concerns.

By combining these metrics and considerations, you can create a robust evaluation framework to assess your fine-tuned LLM’s effectiveness in handling patient conversations about cancer.

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Tiya Vaj

Ph.D. Research Scholar in NLP and my passionate towards data-driven for social good.Let's connect here https://www.linkedin.com/in/tiya-v-076648128/